Selection of projects (1)

Estimating the tracing probability from contact history at the onset of the diseases.

Contact tracing is a control method for infectious diseases. If an infected person is noticed one tries to find more infected persons through the contact history of this index case.  The estimator for the tracing probability developed in the project was applied to tuberculosis and Chlamydia data.

Stochastic modelling for the COMET-assay

A stochastic model for single cell gel electrophoresis (COMET-assay) data has been developed. The distribution of length of DNA fragments was calculated according to a 'Random Breakage Model' and the migration of DNA fragments among gel fibres was modelled. Essential to our approach was the use of point process structures, renewal theory and reduction to intensity histograms for further data analysis. Parameter estimations and simulations illustrated the features of the model.